Tag: Jada Gundy
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Endothelial Tube Maintenance & Analysis in a HUVEC Cell Model for Myotonic Dystrophy Type 1
By Jada Gundy, Arshpreet Brar Faculty Mentor: Ginny Morriss Abstract Myotonic dystrophy type 1 (DM1) is a multi-systemic condition that results in severe muscle weakening and wasting. DM1 is caused by an expanded region of CTG repeats in the DMPK gene, resulting in expression of a toxic CUG repeat-containing RNA. While the primary DM1 mutation…
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The Effects of CUG repeat expression on VEGF signaling in a Cell Culture Model of Myotonic Dystrophy Type 1
By Jada Gundy Faculty Mentor: Ginny Morriss Abstract Myotonic dystrophy type 1 (DM1) is a multi-systemic condition that results in severe muscle weakening and wasting. DM1 is caused by an expanded region of CTG repeats in the DMPK gene, resulting in expression of a toxic CUG repeat-containing RNA. While the primary DM1 mutation is known,…
