Tag: Delaney Baratka
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Localization of Transgenes for Drosophila Models of Myotonic Dystrophy Type 1
By Andrea Waltrip, Delaney Baratka, Shyanne Michael Faculty Mentor: Ginny Morriss Abstract Myotonic Dystrophy Type 1, DM1, is a multi-systemic disorder that results from expression of expanded CTG repeats in the DMPK gene in humans. Three transgenic Drosophila melanogaster lines have been created containing 60, 250, or 480 CTG repeats to model DM1. The transgenic […]
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Investigating the Role of pvr in Drosophila melanogaster DM1-Related Muscle-Wasting
By Victoria Ashton, Delaney Baratka, John Conrad Tan Faculty Mentor: Dr. Ginny Morriss Abstract DM1 is a progressive and multi-systemic muscle-wasting disorder caused by an expansion of CTG repeats in the 3’ UTR region in the DMPK gene. Though the mechanism of how DM1 works is still unknown, research has indicated that PDGFRβ pathway signaling […]
