Category: Poster Presentation
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Computational Determination of Electron-Electron Repulsion and Binding Energy within the Atom
By Docia Atanda, Dorothy Haas Faculty Mentor: Leanna Giancarlo Abstract The atomic binding energy is the energy needed to pull away the innermost electrons in an atom away from the nucleus. The atomic binding energy is a value that takes into account the nuclear charge, electrons, and electrostatic interactions between the two. Using ChemCompute and…
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An Investigation of Intermolecular Forces via Computational Chemistry
By Madison Minvielle, Maria Schneider Faculty Mentor: Leanna Giancarlo Abstract Dipole moments can be investigated through several different methods including determining the polarity and electronegativity of a molecule and analyzing electrostatic maps. Computational chemistry is a useful tool that can calculate the value of a dipole moment without the need for a laboratory experiment. Semi-empirical…
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Using Transition State Theory to Understand the Kinetics for the Gas-Phase Synthesis of Ammonia
By Chloe Boyd, Stephen Case, Abigail Seputro Faculty Mentor: Leanna Giancarlo Abstract To identify the rate-determining step and the most stable transition state for the Haber-Bosch synthesis of gas-phase ammonia, electronic structure calculations for the reactants (N2, H2, NNH2, H2NNH2, HNNH3), intermediates, and transition states were found using the program GAMESS and the basis sets…
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Endothelial Tube Maintenance & Analysis in a HUVEC Cell Model for Myotonic Dystrophy Type 1
By Jada Gundy, Arshpreet Brar Faculty Mentor: Ginny Morriss Abstract Myotonic dystrophy type 1 (DM1) is a multi-systemic condition that results in severe muscle weakening and wasting. DM1 is caused by an expanded region of CTG repeats in the DMPK gene, resulting in expression of a toxic CUG repeat-containing RNA. While the primary DM1 mutation…
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The Effects of CUG repeat expression on VEGF signaling in a Cell Culture Model of Myotonic Dystrophy Type 1
By Jada Gundy Faculty Mentor: Ginny Morriss Abstract Myotonic dystrophy type 1 (DM1) is a multi-systemic condition that results in severe muscle weakening and wasting. DM1 is caused by an expanded region of CTG repeats in the DMPK gene, resulting in expression of a toxic CUG repeat-containing RNA. While the primary DM1 mutation is known,…
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The Effects of Injury on PDGFRβ Expression in a DM1 Context
By Victoria Ashton Faculty Mentor: Dr. Ginny Morriss Abstract Myotonic Dystrophy Type 1 (DM1) is a condition that causes severe weakening and wasting of muscles, caused by an expansion of CTG repeats in the DMPK gene. Previous studies have shown that activation of the protein platelet-derived growth factor receptor beta (PDGFRβ) is deregulated in DM1.…
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The Effects of Estrous Stage on Voluntary Wheel Running and Anxious Behavior in Female CD-1 Mice
By Abigail Algeier and Emily Landry Faculty Mentor: Parrish Waters Abstract Women report having anxiety and other mood disorders at nearly twice the rate of men. The female menstrual cycle involves fluctuations in pituitary hormones, estrogen, and progesterone. Each of these hormones are psychoactive and can potently affect mood state, both acutely and chronically. In…
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The Effects of Estrous Stage on Voluntary Wheel Running and Anxious Behavior in Female CD-1 Mice
By Abigail Algeier and Emily Landry Faculty Mentor: Parrish Waters Abstract Women report having anxiety and other mood disorders at nearly twice the rate of men. The female menstrual cycle involves fluctuations in pituitary hormones, estrogen, and progesterone. Each of these hormones are psychoactive and can potently affect mood state, both acutely and chronically. In…
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Synthesis of KasA Enzyme Inhibitors to Induce Tuberculosis Cell Death
By Carrie Garvey Faculty Mentor: Dr. Davis Oldham Abstract The World Health Organization names TB the 13th leading cause of death and the second leading infectious killer in the world, with current drugs becoming less effective as the cells grow more resistant. The KasA protein in Mycobacterium Tuberculosis (TB) catalyzes a four-step fatty acid elongation…
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Optimization of Adsorption of Methylene Blue Dye on Activated Charcoal
By Abigail Seputro Faculty Mentor: Dr. Leanna Giancarlo Abstract Methylene blue and crystal violet are cationic dyes of high intensity that are commonly discharged in wastewater. The colored compounds in this environment inhibit sunlight penetration in waterways, resulting in the destruction of aquatic ecosystems. Activated carbon offers an attractive option for the efficient removal of…
